Synthesis and Biological Evaluation of Andrographolide C-Glycoside Derivatives as a-Glycosidase Inhibitors

A series of new andrographolide C-glycoside derivatives were synthesized by a facile route. The new com- pounds showed higher potency than the parent andrographolide evaluated as a-glycosidase inhibitors in the pre- liminary study.

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Bibliographic Details
Published in:Chinese journal of chemistry 2012-04, Vol.30 (4), p.914-918
Main Author: 严琳 徐海伟 刘丰五 赵瑾 刘宏民
Format: Article
Language:English
Subjects:
合成
生物评价
穿心莲内酯
糖苷酶抑制剂
衍生物
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Description
Summary:A series of new andrographolide C-glycoside derivatives were synthesized by a facile route. The new com- pounds showed higher potency than the parent andrographolide evaluated as a-glycosidase inhibitors in the pre- liminary study.
ISSN:1001-604X
1614-7065
DOI:10.1002/cjoc.201100179