Cardiac resynchronization therapy in patients with chronic Chagas cardiomyopathy: long-term follow up

Introduction: Chagas disease is a major cause of cardiomyopathy and sudden death in our country. It has a high mortality when their patients develop New York Heart Association (NYHA) class IV. Objective: The objective of this study is to analyze the clinical outcome of patients with Chagas' car...

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Bibliographic Details
Published in:Revista brasileira de cirurgia cardiovascular 2014, Vol.29 (1), p.31-36
Main Authors: Araújo, Edgard Ferreira de, Chamlian, Eduardo Gregório, Peroni, Alexey Pomares, Pereira, Wilson Lopes, Gandra, Sylvio Matheus de Aquino, Rivetti, Luiz Antonio
Format: Article
Language:English
Subjects:
Cardiology
Heart surgery
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Summary:Introduction: Chagas disease is a major cause of cardiomyopathy and sudden death in our country. It has a high mortality when their patients develop New York Heart Association (NYHA) class IV. Objective: The objective of this study is to analyze the clinical outcome of patients with Chagas' cardiomyopathy with congestive heart failure with optimized pharmacological therapy, undergoing cardiac resynchronization therapy. Methods: Between January 2004 and February 2009, 72 patients with Chagas' cardiomyopathy in NYHA class III and IV underwent cardiac resynchronization therapy and were monitored to assess their clinical evolution. We used the t test or the Wilcoxon test to compare the same variable in two different times. A P value < 0.05 was established as statistically significant. Results: The average clinical follow-up was 46.6 months (range 4-79 months). At the end of the evaluation, 87.4% of patients were in NYHA class I or II (P
ISSN:0102-7638
1678-9741
DOI:10.5935/1678-9741.20140008