Drug points: Erythromycin deafness and cimetidine treatment

Audiography showed bilateral hearing loss of 40-60 dB at frequencies of 0.25-8 kHz; hearing returned to normal five days after erythromycin was withdrawn. Since cimetidine inhibits the N-demethylation of erythromycin in vitro, 1 we investigated a possible interaction in six healthy men and two women...

Full description

Saved in:
Bibliographic Details
Published in:BMJ 1994-12, Vol.309 (6969), p.1620-1620
Main Authors: Mogford, N, Pallett, A, George, C
Format: Article
Language:English
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-b272c-fb7b8865bd568c9d189af53531bfd61035107ec977e7dbad9a846e1d47f6aed63
cites
container_end_page 1620
container_issue 6969
container_start_page 1620
container_title BMJ
container_volume 309
creator Mogford, N
Pallett, A
George, C
description Audiography showed bilateral hearing loss of 40-60 dB at frequencies of 0.25-8 kHz; hearing returned to normal five days after erythromycin was withdrawn. Since cimetidine inhibits the N-demethylation of erythromycin in vitro, 1 we investigated a possible interaction in six healthy men and two women aged 19-23.
doi_str_mv 10.1136/bmj.309.6969.1620c
format article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_journals_1777517660</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>4006064751</sourcerecordid><originalsourceid>FETCH-LOGICAL-b272c-fb7b8865bd568c9d189af53531bfd61035107ec977e7dbad9a846e1d47f6aed63</originalsourceid><addsrcrecordid>eNqNkMtOwzAQRS0EEhX0B1hFYp3gieuxDStUykOqxAbWluMHpCJOsd1F_56U8gGsZnHPvSMdQq6ANgAMb7ph0zCqGlSoGsCW2hMygwXKmkvGTsmMKq5qCUyek3nOG0ppy4RUyGfk7iHtPqrt2MeSb6tV2pfPNA5728fKeROiz7ky0VW2H3zpXR99VZI3ZfCxXJKzYL6yn__dC_L-uHpbPtfr16eX5f267lrR2jp0opMSeec4SqscSGUCZ5xBFxwCZRyo8FYJ4YXrjFNGLtCDW4iAxjtkF-T6uLtN4_fO56I34y7F6aUGIQQHgUgnqj1SNo05Jx_0NvWDSXsNVB886cmTnjzpgyf962kq1cfSIfsH_wN2DGnu</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1777517660</pqid></control><display><type>article</type><title>Drug points: Erythromycin deafness and cimetidine treatment</title><source>JSTOR Archival Journals and Primary Sources Collection</source><source>BMJ Publishing</source><creator>Mogford, N ; Pallett, A ; George, C</creator><creatorcontrib>Mogford, N ; Pallett, A ; George, C</creatorcontrib><description>Audiography showed bilateral hearing loss of 40-60 dB at frequencies of 0.25-8 kHz; hearing returned to normal five days after erythromycin was withdrawn. Since cimetidine inhibits the N-demethylation of erythromycin in vitro, 1 we investigated a possible interaction in six healthy men and two women aged 19-23.</description><identifier>ISSN: 0959-8138</identifier><identifier>EISSN: 1468-5833</identifier><identifier>DOI: 10.1136/bmj.309.6969.1620c</identifier><language>eng</language><publisher>London: BMJ Publishing Group LTD</publisher><ispartof>BMJ, 1994-12, Vol.309 (6969), p.1620-1620</ispartof><rights>1994 BMJ Publishing Group Ltd.</rights><rights>Copyright: 1994 (c) 1994 BMJ Publishing Group Ltd.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b272c-fb7b8865bd568c9d189af53531bfd61035107ec977e7dbad9a846e1d47f6aed63</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttp://bmj.com/content/309/6969/1620.4.full.pdf$$EPDF$$P50$$Gbmj$$H</linktopdf><linktohtml>$$Uhttp://bmj.com/content/309/6969/1620.4.full$$EHTML$$P50$$Gbmj$$H</linktohtml><link.rule.ids>112,113,314,776,780,3180,27903,27904,77340,77341</link.rule.ids></links><search><creatorcontrib>Mogford, N</creatorcontrib><creatorcontrib>Pallett, A</creatorcontrib><creatorcontrib>George, C</creatorcontrib><title>Drug points: Erythromycin deafness and cimetidine treatment</title><title>BMJ</title><description>Audiography showed bilateral hearing loss of 40-60 dB at frequencies of 0.25-8 kHz; hearing returned to normal five days after erythromycin was withdrawn. Since cimetidine inhibits the N-demethylation of erythromycin in vitro, 1 we investigated a possible interaction in six healthy men and two women aged 19-23.</description><issn>0959-8138</issn><issn>1468-5833</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1994</creationdate><recordtype>article</recordtype><recordid>eNqNkMtOwzAQRS0EEhX0B1hFYp3gieuxDStUykOqxAbWluMHpCJOsd1F_56U8gGsZnHPvSMdQq6ANgAMb7ph0zCqGlSoGsCW2hMygwXKmkvGTsmMKq5qCUyek3nOG0ppy4RUyGfk7iHtPqrt2MeSb6tV2pfPNA5728fKeROiz7ky0VW2H3zpXR99VZI3ZfCxXJKzYL6yn__dC_L-uHpbPtfr16eX5f267lrR2jp0opMSeec4SqscSGUCZ5xBFxwCZRyo8FYJ4YXrjFNGLtCDW4iAxjtkF-T6uLtN4_fO56I34y7F6aUGIQQHgUgnqj1SNo05Jx_0NvWDSXsNVB886cmTnjzpgyf962kq1cfSIfsH_wN2DGnu</recordid><startdate>19941217</startdate><enddate>19941217</enddate><creator>Mogford, N</creator><creator>Pallett, A</creator><creator>George, C</creator><general>BMJ Publishing Group LTD</general><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88I</scope><scope>8AF</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ASE</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FPQ</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K6X</scope><scope>K9.</scope><scope>LK8</scope><scope>M2O</scope><scope>M2P</scope><scope>M7P</scope><scope>MBDVC</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope></search><sort><creationdate>19941217</creationdate><title>Drug points: Erythromycin deafness and cimetidine treatment</title><author>Mogford, N ; Pallett, A ; George, C</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b272c-fb7b8865bd568c9d189af53531bfd61035107ec977e7dbad9a846e1d47f6aed63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1994</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mogford, N</creatorcontrib><creatorcontrib>Pallett, A</creatorcontrib><creatorcontrib>George, C</creatorcontrib><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>British Nursing Index</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>British Nursing Index (BNI) (1985 to Present)</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>British Nursing Index</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Research Library</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>Research Library (Corporate)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><jtitle>BMJ</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mogford, N</au><au>Pallett, A</au><au>George, C</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Drug points: Erythromycin deafness and cimetidine treatment</atitle><jtitle>BMJ</jtitle><date>1994-12-17</date><risdate>1994</risdate><volume>309</volume><issue>6969</issue><spage>1620</spage><epage>1620</epage><pages>1620-1620</pages><issn>0959-8138</issn><eissn>1468-5833</eissn><abstract>Audiography showed bilateral hearing loss of 40-60 dB at frequencies of 0.25-8 kHz; hearing returned to normal five days after erythromycin was withdrawn. Since cimetidine inhibits the N-demethylation of erythromycin in vitro, 1 we investigated a possible interaction in six healthy men and two women aged 19-23.</abstract><cop>London</cop><pub>BMJ Publishing Group LTD</pub><doi>10.1136/bmj.309.6969.1620c</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0959-8138
ispartof BMJ, 1994-12, Vol.309 (6969), p.1620-1620
issn 0959-8138
1468-5833
language eng
recordid cdi_proquest_journals_1777517660
source JSTOR Archival Journals and Primary Sources Collection; BMJ Publishing
title Drug points: Erythromycin deafness and cimetidine treatment
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-26T18%3A07%3A06IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Drug%20points:%20Erythromycin%20deafness%20and%20cimetidine%20treatment&rft.jtitle=BMJ&rft.au=Mogford,%20N&rft.date=1994-12-17&rft.volume=309&rft.issue=6969&rft.spage=1620&rft.epage=1620&rft.pages=1620-1620&rft.issn=0959-8138&rft.eissn=1468-5833&rft_id=info:doi/10.1136/bmj.309.6969.1620c&rft_dat=%3Cproquest_cross%3E4006064751%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-b272c-fb7b8865bd568c9d189af53531bfd61035107ec977e7dbad9a846e1d47f6aed63%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1777517660&rft_id=info:pmid/&rfr_iscdi=true