Co-proxamol and suicide

EDITOR-We agree with Hawton et al that co-proxamol presents a major overdose hazard, their results illustrating the difficulties for licensing authorities in limiting availability of prescription medicines that are only hazardous in overdose. 1 Co-proxamol is more likely to result in death; it cause...

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Published in:BMJ 2003-07, Vol.327 (7409), p.287-287
Main Authors: Bateman, D N, Afshari, R
Format: Article
Language:English
Subjects:
Letters
Mortality
Narcotics
Opioid analgesics
Pain
Pharmaceutical industry
Poisoning
Prescription drugs
Public health
Suicide
Toxicity
Writing tablets
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container_issue 7409
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container_title BMJ
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creator Bateman, D N
Afshari, R
description EDITOR-We agree with Hawton et al that co-proxamol presents a major overdose hazard, their results illustrating the difficulties for licensing authorities in limiting availability of prescription medicines that are only hazardous in overdose. 1 Co-proxamol is more likely to result in death; it causes prolongation of the QRS interval in an electrocardiogram in experimental animals and in humans. 2 3 This property is usually associated with sodium channel blockade and is a precursor to ventricular arrhythmia.
doi_str_mv 10.1136/bmj.327.7409.287
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1756-1833
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source JSTOR Archival Journals and Primary Sources Collection; BMJ Publishing
subjects Letters
Mortality
Narcotics
Opioid analgesics
Pain
Pharmaceutical industry
Poisoning
Prescription drugs
Public health
Suicide
Toxicity
Writing tablets
title Co-proxamol and suicide
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