NON-MUSCLE INVASIVE BLADDER CANCER RECURRENCE RISK FACTORS

TO ESTABLISH THE RISK OF TUMORAL RECURRENCE FOR NON-MUSCLE INVASIVE BLADDER CANCER (NMIBC) DEPENDINGON HISTOLOGICAL OR ENVIRONMENTAL FACTORS. THE AIM OF THIS PAPER IS TO IMPROVE THE STANDARD CLINICAL CARE IN NMIBC PATIENTS FOLLOW-UP.WE INITIALLY EVALUATED 987 PATIENTS DIAGNOSED WITH BLADDER CANCER B...

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Published in:Research and science today 2016-03, Vol.11 (1), p.139-146
Main Authors: Dragoescu, Octavian, Drocas, Andrei Ioan, Mitroi, George, Mititelu, Cosmin, Gaman, Alice Elena, Ungureanu, Anca, Tomescu, Paul
Format: Article
Language:English
Subjects:
Age
Bacteriology
Bladder
Bladder cancer
Cancer
General Reference Works
Health and medicine and law
Health risk assessment
Health risks
Invasiveness
Medicine
Muscles
Parasitology
Pharmacy
Risk analysis
Risk factors
Smoking
Tumors
Urology
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Summary:TO ESTABLISH THE RISK OF TUMORAL RECURRENCE FOR NON-MUSCLE INVASIVE BLADDER CANCER (NMIBC) DEPENDINGON HISTOLOGICAL OR ENVIRONMENTAL FACTORS. THE AIM OF THIS PAPER IS TO IMPROVE THE STANDARD CLINICAL CARE IN NMIBC PATIENTS FOLLOW-UP.WE INITIALLY EVALUATED 987 PATIENTS DIAGNOSED WITH BLADDER CANCER BETWEEN JANUARY 2005 AND DECEMBER 2014. MUSCLE-INVASIVE BLADDER CANCER (MIBC) WAS DIAGNOSED FOR 309 PATIENTS (31.3%) WHILE 678 (68.7%) HAD NMBIC. A TOTAL OF 540 PATIENTS WITH NMIBC WERE ANALYZED IN THE STUDY, WHILETHE OTHER 138 (20.4%) WERE EXCLUDED DUE TO INCOMPLETE CLINICAL DATA OR FOLLOW-UP. THE RETROSPECTIVE STUDYANALYZED PATIENTS’ CHARTS, DISCHARGE NOTES, ONCOLOGY REPORTS. PATIENTS WITH AT LEAST 3 YEARS COMPLETEFOLLOW-UP DATA WERE ENROLLED.THE AVERAGE AGE OF DIAGNOSED PATIENTS WITH NMIBC WAS 65.3 YEARS. THEMAJORITY OF PATIENTS WERE DIAGNOSED WITH SINGLE TUMORS (68.5%). NMIBC WAS PREDOMINANT IN MALES, WITH A SEXRATIO 3.25:1 FOR MALES. BLADDER TRIGON IS THE MAIN LOCATION FOR BLADDER TUMORS. SMOKING WAS THE MAIN RISKFACTOR ACCORDING TO OUR RESULTS. SMOKERS HAD A 4 TIMES HIGHER RISK FOR NMIBC DEVELOPMENT. PATIENTS WITHMULTIPLE BLADDER TUMORS HAD 2.28 HIGHER RISK OF RECURRENCE. OVERALL RECURRENCE FOR NMIBC WAS 49.1%.SMOKING IS THE MOST IMPORTANT RISK FACTOR AND THE RECURRENCE RATE IS HIGHER IN SMOKING-PATIENTS.ALSO,PATIENTS WITH MULTIPLE TUMOURS HAVE BEEN DIAGNOSED WITH HIGHER RISK FOR TUMOR RECURRENCE (P
ISSN:2247-4455
2285-9632