Neutropenia Due to Very Long Time Propylthiouracil Usage in Toxic Multinodular Goiter

Thyrotoxicosis affects hematopoiesis in several ways and thioamides may cause myelosuppression. We report a case of febrile neutropenia in a patient with hyperthyroidism who was using propylthiouracil for nearly 20 years for the treatment of toxic multinodular goitre. After surgery, the patient was...

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Bibliographic Details
Published in:Turkish journal of endocrinology and metabolism 2016-03, Vol.20 (1)
Main Authors: Turan, Elif, Kaya, Ahmet, Kulaksizoglu, Mustafa, Kandemir, Bahar, Erayman, Ibrahim
Format: Article
Language:English
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Summary:Thyrotoxicosis affects hematopoiesis in several ways and thioamides may cause myelosuppression. We report a case of febrile neutropenia in a patient with hyperthyroidism who was using propylthiouracil for nearly 20 years for the treatment of toxic multinodular goitre. After surgery, the patient was euthyroid and neutropenia resolved. Postoperative pathology was evaluated as micropapillary thyroid carcinoma.
ISSN:1301-2193
1308-9846
DOI:10.4274/tjem.2821