Circulating tumor cells in oral squamous cell carcinoma: An insight

Circulating tumor cells (CTCs) are those cells present in the blood and have antigenic and/or genetic characteristics of a specific tumor type. CTCs can be detected in the peripheral blood of cancer patients. Various techniques are available for detection of CTCs, which provide evidence for future m...

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Bibliographic Details
Published in:Indian journal of cancer 2015-04, Vol.52 (2), p.232
Main Authors: Prakruthi, B, Babu, N
Format: Article
Language:English
Subjects:
Cancer research
Care and treatment
Genetic aspects
Mouth cancer
Precision medicine
Squamous cell carcinoma
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Summary:Circulating tumor cells (CTCs) are those cells present in the blood and have antigenic and/or genetic characteristics of a specific tumor type. CTCs can be detected in the peripheral blood of cancer patients. Various techniques are available for detection of CTCs, which provide evidence for future metastasis. CTCs may provide new insight into the biology of cancer and process of metastasis in oral squamous cell carcinoma (OSCC). The detection of CTCs may represent a new diagnostic tool for predicting the occurrence of metastatic disease in OSCC and endow with the treatment strategies to efficiently treat and prevent cancer metastasis. This review gives an insight into the significance of CTCs and different techniques for detection of CTCs.
ISSN:0019-509X
1998-4774
DOI:10.4103/0019-509X.175844