The bacteriophage 29 tail possesses a pore-forming loop for cell membrane penetration

Structural and functional studies of the tail knob protein of bacteriophage [phi]29 shed light on how the phage breaches the membrane barrier and ejects its DNA genome into the host cell.

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Bibliographic Details
Published in:Nature (London) 2016-06, Vol.534 (7608), p.544
Main Authors: Xu, Jingwei, Gui, Miao, Wang, Dianhong, Xiang, Ye
Format: Article
Language:English
Subjects:
Analysis
Bacteria
Bacteriophages
Botanical research
Cell membranes
Crystals
Deoxyribonucleic acid
DNA
Genetic aspects
Genomes
Genomics
Membrane lipids
Membranes
Physiological aspects
Plant physiology
Polypeptides
Proteins
Structure
Tail
Virology
Viruses
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Description
Summary:Structural and functional studies of the tail knob protein of bacteriophage [phi]29 shed light on how the phage breaches the membrane barrier and ejects its DNA genome into the host cell.
ISSN:0028-0836
1476-4687
DOI:10.1038/nature18017