Facile synthesis, characterization and antimicrobial activities of diphenylphosphoryl derivatives of substituted aryl and nitrogen heterocycles

Diphenylphosphoryl derivatives of substituted aryl and nitrogen heterocycles were prepared by a one-pot process involving sequential reaction of diphenylphosphine chloride with dry methyl alcohol/ethyl alcohol and then with different halides of substituted nitrogen heterocycles/aryl halides. The tit...

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Bibliographic Details
Published in:Organic communications 2013-01, Vol.6 (1), p.41
Main Authors: G Subba Reddy, K Uma Maheswara Rao, S Santhi Sudha, N Bakthavatchala Reddy, Ch Syama Sundar, C Naga Raju, Reddy, C Suresh
Format: Article
Language:English
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Summary:Diphenylphosphoryl derivatives of substituted aryl and nitrogen heterocycles were prepared by a one-pot process involving sequential reaction of diphenylphosphine chloride with dry methyl alcohol/ethyl alcohol and then with different halides of substituted nitrogen heterocycles/aryl halides. The title compounds (5a-j) structures were established by analytical, IR, NMR ( 1H, 13C and 31P) and mass spectra, and they have been screened for their antimicrobial activity. They exhibited significant antibacterial and antifungal activity.
ISSN:1307-6175