Effect of regular intake of vitamin-mineral complex on spontaneous and on induced clustogenesis in humans

Regular intake of a vitamin-mineral complex for 2 weeks had no effect on spontaneous clustogenesis in blood cells from healthy donors. Significant differences between the levels of chromosome aberrations induced by bleomycin and dioxidine in vitro before and after 2-week vitamin treatment indicate i...

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Bibliographic Details
Published in:Bulletin of experimental biology and medicine 2000-09, Vol.130 (9), p.867
Main Authors: Nikitina, V A, Vrzhesinskaya, O A, Beketova, N A, Pereverzeva, O G, Kharitonchik, L A, Isaeva, V A, Kodentsova, V M, Spirichev, V B, Durnev, A D
Format: Article
Language:English
Subjects:
Adult
Anti-Bacterial Agents - toxicity
Bleomycin - toxicity
Chromosome Aberrations
Drug Antagonism
Female
Humans
Lymphocytes - drug effects
Male
Middle Aged
Mutagens - toxicity
Quinoxalines - toxicity
Vitamins - administration & dosage
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Summary:Regular intake of a vitamin-mineral complex for 2 weeks had no effect on spontaneous clustogenesis in blood cells from healthy donors. Significant differences between the levels of chromosome aberrations induced by bleomycin and dioxidine in vitro before and after 2-week vitamin treatment indicate increased resistance of blood cells to clustogens.
ISSN:0007-4888
1573-8221
DOI:10.1023/A:1015314212167