Comparison of GFAP and HSP27 concentrations in acute moderate-intensity aerobic exercise of different duration

• Published in: Medical journal of Indonesia 2016-07, Vol.25 (2), p.112-7
• Main Authors: Stefanus, Robert, Yolanda, Sophie, Antarianto, Radiana D.
• Format: Article
• Language: English
• ISSN: 0853-1773; 2252-8083
• DOI: 10.13181/mji.v25i2.1267

Background: Glial fibrillary acidic protein (GFAP) and heat shock protein -27 (HSP27) plasma can be used as the parameters of exercise-induced astrocyte reactivity. The American College of Sports Medicine (ACSM) recommends an exercise of 30 minutes or 10 minutes duration (each performing bout accumulated toward 30 minutes). The aim of this study was to compare GFAP and HSP27 plasma concentrations in young adults undergoing acute moderate-intensity aerobic exercise of different durations (10 minutes vs 30 minutes).Methods: An experimental study with pre-post design was conducted on 22 participants assigned to either 10 minutes or 30 minutes duration of single bout exercise. Blood sampling was performed before and after the exercise. GFAP and HSP27 plasma levels were measured with ELISA methods. Plasma GFAP and HSP27 levels before and after exercise were analyzed using paired t -test, while GFAP and HSP27 levels after exercise between the two groups were processed using unpaired t-test.Results: Plasma GFAP concentration decreased significantly (0,45 ng/mL) after 30 minutes of aerobic exercise (p