Baseline level of 30-min plasma glucose is an independent predictor of incident diabetes among Asian Indians: analysis of two diabetes prevention programmes

• Published in: Diabetes/metabolism research and reviews 2016-10, Vol.32 (7), p.762-767
• Main Authors: Chamukuttan, Snehalatha, Ram, Jagannathan, Nanditha, Arun, Shetty, Ananth Samith, Sevick, Mary Ann, Bergman, Michael, Johnston, Desmond G., Ramachandran, Ambady
• Format: Article
• Language: English
• Subjects: 30-min plasma glucose; Adult; Asian Indian; Biomarkers - blood; Blood Glucose - metabolism; Case-Control Studies; Diabetes; Diabetes Mellitus - blood; Diabetes Mellitus - epidemiology; Diabetes Mellitus - prevention & control; Fasting; Fasting - blood; Female; Follow-Up Studies; Glucose; Glucose Intolerance - blood; Glucose Intolerance - epidemiology; Glucose Intolerance - prevention & control; Glucose Tolerance Test; Glycated Hemoglobin A - analysis; Humans; impaired glucose tolerance; incidence of diabetes; India - epidemiology; Male; Middle Aged; oral glucose tolerance test; Prediabetic State - blood; Prediabetic State - epidemiology; Prediabetic State - prevention & control; Predictive Value of Tests; Prevalence; Prospective Studies; Risk Factors; Time Factors; type 2 diabetes
• ISSN: 1520-7552; 1520-7560
• DOI: 10.1002/dmrr.2799

Background The objective was to study the ability of the 30‐min plasma glucose (30‐min PG) during an oral glucose tolerance test to predict the future risk of type 2 diabetes among Asian Indians with impaired glucose tolerance. Methods For the present analyses, we utilized data from 753 participants from two diabetes primary prevention studies, having complete data at the end of the study periods, including 236 from Indian Diabetes Prevention Programme‐1 and 517 from the 2013 study. Baseline 30‐min PG values were divided into tertiles: T1