GW27-e0526 Plasma level of big endothelin-1 in patients with hypertrophic cardiomyopathy

After adjusting for multiple factors related to survival and cardiac function, the significance remained in the association of big endothelin-1 with the risk of all-cause mortality (hazard ratio (HR) = 1.72, 95% confidence interval (CI) 1.11-2.67, p=0.016) heart failure-related death (HR = 1.86, 95%...

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Bibliographic Details
Published in:Journal of the American College of Cardiology 2016-10, Vol.68 (16), p.C158-C158
Main Authors: Yilu, Wang, Zou, Yubao, Luo, Xiaoliang, Kang, Lianming, Wang, Dong, Wu, Guixin, Wang, Hu, Hui, Rutai, Wang, Jizheng, Tang, Yida, Song, Lei
Format: Article
Language:English
Subjects:
Beta blockers
Cardiology
Cardiomyopathy
Cardiovascular
Cardiovascular disease
Health risk assessment
Heart failure
Internal Medicine
Medical prognosis
Mortality
Plasma
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Summary:After adjusting for multiple factors related to survival and cardiac function, the significance remained in the association of big endothelin-1 with the risk of all-cause mortality (hazard ratio (HR) = 1.72, 95% confidence interval (CI) 1.11-2.67, p=0.016) heart failure-related death (HR = 1.86, 95%CI 1.08-3.19, p=0.025) and progression to heart failure (HR = 1.48, 95%CI 1.01-2.16, p=0.043).
ISSN:0735-1097
1558-3597
DOI:10.1016/j.jacc.2016.07.595