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GW27-e0997 Effect of NOD1/RIP2 signaling pathway on cardiovascular remodeling in hypertensive rats

Objectives The innate immune systems and its mediated inflammatory responses play a prominent role in the initiation and maintenance of hypertension and significantly contributes to target organ damage and mortality.NOD1 receptor is an innate immune pattern recognition receptor, and play an importan...

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Bibliographic Details
Published in:Journal of the American College of Cardiology 2016-10, Vol.68 (16), p.C35-C35
Main Authors: Bingqian, Fang, Hou, Liang, Lu, Yingjin, Liu, Jinli, Liu, Wei, Zhang, Xiuzhen, Cheng, Xu, Chang, Jingjie, Sun, Lingmin, Wang, Xiuli, Ding, Yanchun
Format: Article
Language:English
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Summary:Objectives The innate immune systems and its mediated inflammatory responses play a prominent role in the initiation and maintenance of hypertension and significantly contributes to target organ damage and mortality.NOD1 receptor is an innate immune pattern recognition receptor, and play an important role in the pathogenesis of many inflammatory diseases.
ISSN:0735-1097
1558-3597
DOI:10.1016/j.jacc.2016.07.130