New phosphorus dithioacids and their derivatives containing chiral centers and pharmacophoric groups

New phosphorus dithioacids, their ammonium salts and S-silyl and plumbyl derivatives containing asymmetric carbon atoms and pharmacophoric groups were obtained by the reactions of tetraphosphorus decasulfide and 1,3,2,4-dithiadiphosphetane-2,4-disulfides with chiral natural terpenyl alcohols, diols,...

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Bibliographic Details
Published in:Phosphorus, sulfur, and silicon and the related elements sulfur, and silicon and the related elements, 2016-12, Vol.191 (11-12), p.1578-1580
Main Authors: Nizamov, I. S., Terenzhev, D. A., Sabirzyanova, G. R., Salikhov, R. Z., Nizamov, I. D., Cherkasov, R. A.
Format: Article
Language:English
Subjects:
Biological activity
chirality
dithiophosphorylation
pharmacophoric
Phosphorus
Phosphorus dithioacids
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Summary:New phosphorus dithioacids, their ammonium salts and S-silyl and plumbyl derivatives containing asymmetric carbon atoms and pharmacophoric groups were obtained by the reactions of tetraphosphorus decasulfide and 1,3,2,4-dithiadiphosphetane-2,4-disulfides with chiral natural terpenyl alcohols, diols, carboxylic acid esters, amino acids and monosaccharides as well as synthetic chiral amines and 1-phenylethanol. The biological activity of the ammonium salts and S-esters of phosphorus dithioacids were studied.
ISSN:1042-6507
1563-5325
DOI:10.1080/10426507.2016.1216418