Comparison of intubation conditions with halothane suxamethonium and halothane topical lidocaine 2% in children undergoing

Background Suxamethonium has several side effects, particularly in children, including apnea, bradycardia, hyperkalemia, and the fatal side effect malignant hyperthermia. Looking for a safe, available and cheap alternative to suxamethonium is the aim of this study. Patients and Methods Sixty childre...

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Bibliographic Details
Published in:Research and Opinion in Anesthesia & Intensive Care 2015-07, Vol.2 (3), p.85
Main Authors: Khalifa, OsamaYA, Saadalla, AymanET
Format: Article
Language:English
Subjects:
Anesthesia
Blood pressure
Drug dosages
Heart rate
Intubation
Respiratory therapy
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Summary:Background Suxamethonium has several side effects, particularly in children, including apnea, bradycardia, hyperkalemia, and the fatal side effect malignant hyperthermia. Looking for a safe, available and cheap alternative to suxamethonium is the aim of this study. Patients and Methods Sixty children admitted for adenoidotonsillectomy aged between 3 and 8 years were classified into two groups. Group HS was formed of 30 patients anesthetized using inhalational halothane 5% and suxamethonium 1.5 mg/kg. Group HL was formed of 30 patients who were anesthetized with halothane 5% and topical oral lidocaine solution 2% at a dose of 4 mg/kg. The intubation conditions score was applied in both groups. Results There was a nonsignificant difference between the two groups as regards the hemodynamic parameters both before and after intubation. There was also a nonsignificant difference in intubation conditions score between the two groups. Conclusion Lidocaine 2% oral solution at a dose of 4 mg/kg before intubation produces similar hemodynamics and intubation conditions to suxamethonium in adenoidotonsillectomy in children aged 3-8 years.
ISSN:2356-9115
2356-9123
DOI:10.4103/2356-9115.172798