Vitamin D supplementation trial in infancy: body composition effects at 3years of age in a prospective follow-up study from Montréal

Summary Background The impact of vitamin D status on body composition is not well understood. Objectives Evaluate how vitamin D supplementation in infancy affects body composition at 3years of age. Methods Double-blind randomized trial of 132, 1-month-old healthy, breastfed infants randomly assigned...

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Bibliographic Details
Published in:Pediatric obesity 2017-02, Vol.12 (1), p.38
Main Authors: Hazell, T J, Gallo, S, Vanstone, C A, Agellon, S, Rodd, C, Weiler, H A
Format: Article
Language:English
Subjects:
Age
Babies
Body composition
Childrens health
Obesity
Pediatrics
Vitamin D
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Summary:Summary Background The impact of vitamin D status on body composition is not well understood. Objectives Evaluate how vitamin D supplementation in infancy affects body composition at 3years of age. Methods Double-blind randomized trial of 132, 1-month-old healthy, breastfed infants randomly assigned to receive oral vitamin D3 supplements of 400, 800, 1200 or 1600IUd-1 for 11months. In the present analysis, 87 (66%) returned at 3years of age. Body composition was measured using dual-energy x-ray absorptiometry and plasma 25-hydroxyvitamin D [25(OH)D] concentrations by liquid chromatography tandem mass spectrometry. Results Anthropometry, body composition, diet, activity and demographics were similar across dosage groups at 3years. Mean 25(OH)D concentration from 1month to 3years was higher (P
ISSN:2047-6302
2047-6310
DOI:10.1111/ijpo.12105