Mast cell Tryptase and Carboxypeptidase A3 (CPA3) as Markers for Predicting Susceptibility to Severe Allergic Drug Reactions

Sensitive enzyme linked immunosorbent assays (ELISA) were developed and validated, using specific antibodies to tryptase and CPA3 (lower limits of detection of 0.4 ng/ml and 0.2 ng/ml, respectively), and applied to serum and saliva samples.

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Bibliographic Details
Published in:Journal of allergy and clinical immunology 2017-02, Vol.139 (2), p.AB39-AB39
Main Authors: Abadalkareem, Rana, MBBS, Lau, Laurie C.K., PhD, Abdelmotelb, Ahmed, PhD, Zhou, Xiaoying, PhD, Eren, Efrem, MBBS, PhD, Walls, Andrew F., PhD, FAAAAI
Format: Article
Language:English
Subjects:
Allergies
Allergy and Immunology
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Description
Summary:Sensitive enzyme linked immunosorbent assays (ELISA) were developed and validated, using specific antibodies to tryptase and CPA3 (lower limits of detection of 0.4 ng/ml and 0.2 ng/ml, respectively), and applied to serum and saliva samples.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2016.12.185