Successful Utilization of Costimulatory Blockade in a Refractory Pediatric Autoimmune Enteropathy Patient

Rationale Autoimmune enteropathy (AIE) is a rare disorder involving a T cell regulatory defect, resulting in enterocyte destruction and small intestinal mucosal atrophy with anti enterocyte antibodies.

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Bibliographic Details
Published in:Journal of allergy and clinical immunology 2017-02, Vol.139 (2), p.AB209-AB209
Main Authors: Kleiner, Gary I., MD, PhD, FAAAAI, Langshaw, Amber H., MD, Rivera, Edgardo Rivera, MD, Gebbia, Jennifer, ARNP, Rodriguez, Maria, RN, Simon, Nancy, PharmD
Format: Article
Language:English
Subjects:
Allergy and Immunology
Diarrhea
Lymphocytes
Pediatrics
Online Access:Get full text
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Description
Summary:Rationale Autoimmune enteropathy (AIE) is a rare disorder involving a T cell regulatory defect, resulting in enterocyte destruction and small intestinal mucosal atrophy with anti enterocyte antibodies.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2016.12.677