Identification of Asthma Phenotypes Among Older Adults with Persistent Asthma

Results Four main clusters were identified: cluster 1 had the shortest duration of asthma with 82.1 % population diagnosed after age 40; cluster 2 was the healthiest based on least number of comorbidities, lowest BMI, least fixed airway obstruction, lowest oral steroid use, highest spirometry, highe...

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Bibliographic Details
Published in:Journal of allergy and clinical immunology 2017-02, Vol.139 (2), p.AB170-AB170
Main Authors: Karamched, Keerthi, MD, Carpenter, Laurie, BS, MSW, Hao, Wei, BS, MA, Kaur, Bani Preet, MD, Baptist, Alan P., MD, MPH
Format: Article
Language:English
Subjects:
Airway management
Allergy and Immunology
Asthma
Cluster analysis
Older people
Quality of life
Online Access:Get full text
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Summary:Results Four main clusters were identified: cluster 1 had the shortest duration of asthma with 82.1 % population diagnosed after age 40; cluster 2 was the healthiest based on least number of comorbidities, lowest BMI, least fixed airway obstruction, lowest oral steroid use, highest spirometry, highest ACT and asthma quality of life scores; cluster 3 had the longest duration of asthma (55.2 years) with 2.3% population diagnosed after age 40, highest BMI (32.5), and highest rhinitis rates (86.1%); cluster 4 was the unhealthiest based on greatest number of comorbidities, most fixed airway obstruction, lowest spirometric findings, lowest ACT and asthma quality of life scores.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2016.12.559