Ibrutinib, a BTK inhibitor used for treatment of lymphoproliferative disorders, eliminates both aeroallergen skin test and basophil activation test reactivity in allergic cancer patients receiving drug

[...]BAT responses to a non-IgE-dependent stimulus, formyl-methionyl-leucyl-phenylalanine, were unaffected or minimally altered.

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Bibliographic Details
Published in:Journal of allergy and clinical immunology 2017-02, Vol.139 (2), p.AB232-AB232
Main Authors: Regan, Jennifer A., MD, PhD, Petrich, Adam M., MD, Dispenza, Melanie C., MD, PhD, Ma, Shuo, MD, PhD, Gordon, Leo I., MD, Bochner, Bruce S., MD, FAAAAI
Format: Article
Language:English
Subjects:
Allergies
Allergy and Immunology
Online Access:Get full text
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Description
Summary:[...]BAT responses to a non-IgE-dependent stimulus, formyl-methionyl-leucyl-phenylalanine, were unaffected or minimally altered.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2016.12.748