Astroblastoma: a rare case report

Background An astroblastoma is a rare primary glial tumour occurring preferentially in young adults. It is characterised by a perivascular arrangement of tumour cells forming perivascular pseudorosettes mimicking ependymomas. The histogenesis of astroblastoma is unclear. Case description We present...

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Bibliographic Details
Published in:Journal of radiotherapy in practice 2016-03, Vol.15 (1), p.107-110
Main Authors: Palled, Siddanna R., Thimmaya, Naveen, Jagadheesan, Sugashwaran, Khaleel, Ibrahim
Format: Article
Language:English
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Case Study
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Summary:Background An astroblastoma is a rare primary glial tumour occurring preferentially in young adults. It is characterised by a perivascular arrangement of tumour cells forming perivascular pseudorosettes mimicking ependymomas. The histogenesis of astroblastoma is unclear. Case description We present the history of a 13-year-old girl with chief complaints of headache associated with vomiting, blurring of vision on the left eye and a history of diplopia on the right eye. She underwent left parietal parasagittal craniotomy and near-total excision of tumour. She was planned for postoperative radiotherapy 5,940 cGy in 28 fractions along with concurrent temozolamide100 mg. She had no neurological deficit or complaints during her last visit. Conclusion Astroblastomas are a distinct clinic pathologic entity, with well-described radiologic, pathologic and cytogenetic features. Its recurrence is high, and efforts must be made to elucidate the role and usefulness of radiotherapy and chemotherapy in these tumours.
ISSN:1460-3969
1467-1131
DOI:10.1017/S1460396915000485