Improvement of the desorption of the pesticide 2,4-D via complexation with HP-β-cyclodextrin

• Published in: Pest management science 2000-05, Vol.56 (5), p.425-430
• Main Authors: Pérez-Martínez, José I, Ginés, Juan M, Morillo, Esmeralda, González-Rodríguez, María L, Moyano Méndez, José R
• Format: Article
• Language: English
• Subjects: 2,4‐D; 4-D; Agronomy. Soil science and plant productions; Biological and medical sciences; Chemical control; complex formation; cyclodextrins; desorption; Fundamental and applied biological sciences. Psychology; Parasitic plants. Weeds; Phytopathology. Animal pests. Plant and forest protection; Soil and water pollution; Soil science; Weeds
• ISSN: 1526-498X; 1526-4998
• DOI: 10.1002/(SICI)1526-4998(200005)56:5<425::AID-PS156>3.0.CO;2-W

Inclusion complex formation of 2,4‐dichlorophenoxyacetic acid (2,4‐D) with hydroxypropyl‐β‐cyclodextrin (HP‐β‐CD) has been proposed as a way of modifying the behaviour of the pesticide in the soil environment. The present study assesses the effect of complex formation on 2,4‐D physicochemical properties (aqueous solubility, crystallinity and dissolution rate) and its behaviour on soils. The solid complexes were prepared using different methods (spray drying, kneading and heating in a sealed container). To confirm the complex formation in the solid state differential scanning calorimetry, hot stage microscopy and x‐ray diffraction techniques were employed. Complex formation in solution was studied by phase solubility. The presence of HP‐β‐CD increased the 2,4‐D solubility nine times approximately. The apparent stability constant was determined as 98.6 M −1. The dissolution rates of the 2,4‐D/HP‐β‐CD complexes were examined and compared with that of the pure pesticide. The results indicated that the complex may have great utility as a rapid way of dissolving the pesticide. Batch experiments were performed to study the adsorption–desorption of 2,4‐D on soils and the influence of the HP‐β‐CD over these processes. The results showed that HP‐β‐CD could increase the desorption of 2,4‐D previously adsorbed on soils. © 2000 Society of Chemical Industry