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APELIN-13 CO-TREATMENT WITH UMBILICAL CORD BLOOD-DERIVED MESENCHYMAL STEM CELLS IMPROVES ENGRAFTED CELL SURVIVAL AND INHIBITS MACROPHAGE ACTIVATION IN PULMONARY ARTERIAL HYPERTENSION MURINE MODEL

Two weeks after hUCB-MSC treatment, (1) RV hemodynamics was determined by echocardiography, (2) pulmonary arterial media wall thickness and fibrosis by histological assessment, and (3) genes related to macrophage activation by quantitative real-time PCR.

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Bibliographic Details
Published in:Journal of the American College of Cardiology 2017-03, Vol.69 (11), p.1900-1900
Main Authors: Jang, Albert, Oh, Seyeon, Choi, Seungbum, Chae, Sehyun, Moon, Jeongsik, Kim, Minsu, Oh, Pyung Chun, Lee, Kyunghoon, Son, Kuk Hui, Hwang, Daehee, Byun, Kyunghee, Chung, Wook-Jin
Format: Article
Language:English
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Summary:Two weeks after hUCB-MSC treatment, (1) RV hemodynamics was determined by echocardiography, (2) pulmonary arterial media wall thickness and fibrosis by histological assessment, and (3) genes related to macrophage activation by quantitative real-time PCR.
ISSN:0735-1097
1558-3597
DOI:10.1016/S0735-1097(17)35289-0