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Design and synthesis of basic ionic liquids for the esterification of triterpenic acids

We present the design and synthesis of Brønsted-basic ionic liquids and investigate their application in the microwave-assisted esterification of betulinic acid, aiming towards a benign and pyridine-free manufacturing process of the anti-HIV drug, bevirimat. Graphical abstract

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Bibliographic Details
Published in:Monatshefte für Chemie 2017, Vol.148 (1), p.139-148
Main Authors: Ressmann, Anna K., Schneider, Maria, Gaertner, Peter, Weil, Matthias, Bica, Katharina
Format: Article
Language:English
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Summary:We present the design and synthesis of Brønsted-basic ionic liquids and investigate their application in the microwave-assisted esterification of betulinic acid, aiming towards a benign and pyridine-free manufacturing process of the anti-HIV drug, bevirimat. Graphical abstract
ISSN:0026-9247
1434-4475
DOI:10.1007/s00706-016-1889-1