Copper(II) acetate monohydrate: an efficient and eco-friendly catalyst for the one-pot multi-component synthesis of biologically active spiropyrans and 1H-pyrazolo[1,2-b]phthalazine-5,10-dione derivatives under solvent-free conditions

We have studied the catalytic ability of copper(II) acetate monohydrate as a mild, environmentally benign, natural and economical catalyst for the multi-component efficient synthesis of biologically active spiro-4 H -pyran derivatives and 1 H -pyrazolo[1,2-b]phthalazine-5,10-dione derivatives with e...

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Bibliographic Details
Published in:Research on chemical intermediates 2016-12, Vol.42 (12), p.7841-7853
Main Authors: Mohamadpour, Farzaneh, Maghsoodlou, Malek Taher, Heydari, Reza, Lashkari, Mojtaba
Format: Article
Language:English
Subjects:
Catalysis
Catalysts
Chemical synthesis
Chemistry
Chemistry and Materials Science
Copper acetate
Inorganic Chemistry
Physical Chemistry
Solvents
Spiropyrans
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Summary:We have studied the catalytic ability of copper(II) acetate monohydrate as a mild, environmentally benign, natural and economical catalyst for the multi-component efficient synthesis of biologically active spiro-4 H -pyran derivatives and 1 H -pyrazolo[1,2-b]phthalazine-5,10-dione derivatives with excellent yields and short reaction times. The most important advantages of this procedure are its mild, non-toxic and inexpensive catalyst, one-pot synthesis, environmentally benign nature, solvent-free conditions, simple operational procedures, and highly efficient conditions. Graphical Abstract
ISSN:0922-6168
1568-5675
DOI:10.1007/s11164-016-2565-0