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Single cell tells the developmental story

Stem cells are undifferentiated cells that retain the ability to self-renew and differentiate into specialized cells, offering a promising resource to generate requisite cell types in regenerative medicine [1, 2]. Haematopoietic stem cells (HSCs) can differentiate into entire mature blood lineages,...

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Bibliographic Details
Published in:Science bulletin (Beijing) 2016-09, Vol.61 (17), p.1355-1357
Main Authors: Zhan, Zhengyan, Xu, Xin, Fu, Yu V.
Format: Article
Language:English
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Summary:Stem cells are undifferentiated cells that retain the ability to self-renew and differentiate into specialized cells, offering a promising resource to generate requisite cell types in regenerative medicine [1, 2]. Haematopoietic stem cells (HSCs) can differentiate into entire mature blood lineages, sitting at the apex of the haematopoietic hierachy and playing a key role in the long-term maintenance and stabilization of mammalian blood system functions [3, 4].
ISSN:2095-9273
2095-9281
DOI:10.1007/s11434-016-1153-4