Trends in Spoligotype Patterns of Mycobacterium tuberculosis Strains in Central India

This study aims to understand trends in spoligotype patterns of Mycobacterium tuberculosis (MTB) in Central India. Elucidation of these trends may provide baseline information to understand the transmission dynamics of strains of MTB in the region. Spoligotyping was carried out on 340 MTB strains is...

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Bibliographic Details
Published in:Indian journal of medical microbiology 2017-01, Vol.35 (1), p.129-133
Main Authors: Desikan, Prabha, Chauhan, Devendra S., Panwalkar, Nikita, Sharma, Pragya, Yadav, Priyanka
Format: Article
Language:English
Subjects:
Central India
Mycobacterium tuberculosis
spoligotype patterns
trends
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Summary:This study aims to understand trends in spoligotype patterns of Mycobacterium tuberculosis (MTB) in Central India. Elucidation of these trends may provide baseline information to understand the transmission dynamics of strains of MTB in the region. Spoligotyping was carried out on 340 MTB strains isolated from clinical samples received from 2007 to 2011. The prevalence of ST26/CAS1_Del, ST11/EAI3_IND, ST288/CAS2, ST25/CAS1_Del and Beijing lineages showed waxing and waning trends. ST26/CAS1_Del and ST11/EAI3_IND lineages were consistently present and were predominant. Well-established lineages showed a consistent presence in the community. New orphan lineages appeared to be less capable of establishing themselves.
ISSN:0255-0857
1998-3646
DOI:10.4103/ijmm.IJMM_16_12