RETRACTED ARTICLE: MiR-154 Functions as a Tumor Suppressor in Glioblastoma by Targeting Wnt5a

Recently, deregulated microRNA (miRNA) expression contributes to the development and progression of human glioblastoma. The aim of the present study was to evaluate the level of miR-154 and Wnt5a in glioblastoma tissues and cells. We further investigated the molecular mechanisms of miR-154 and Wnt5a...

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Bibliographic Details
Published in:Molecular neurobiology 2017-05, Vol.54 (4), p.2823-2830
Main Authors: Zhao, Dongsheng, Wang, Rencong, Fang, Junkang, Ji, Xituan, Li, Juan, Chen, Xiaoyan, Sun, Gangfeng, Wang, Zhengjun, Liu, Weiping, Wang, Yangang, Cheng, Guang, Zhen, Haining, Sun, Chunhua, Fei, Zhou
Format: Article
Language:English
Subjects:
Biomedical and Life Sciences
Biomedicine
Cell Biology
Neurobiology
Neurology
Neurosciences
Tissues
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Summary:Recently, deregulated microRNA (miRNA) expression contributes to the development and progression of human glioblastoma. The aim of the present study was to evaluate the level of miR-154 and Wnt5a in glioblastoma tissues and cells. We further investigated the molecular mechanisms of miR-154 and Wnt5a in glioblastoma cell lines. In the present study, we found that miR-154 expression was downregulated in glioblastoma tissues and U87, U251, and A172 cells (all p  
ISSN:0893-7648
1559-1182
DOI:10.1007/s12035-016-9867-5