Plasticity of Mycoplasmas: Changes in the Genomic Profile, as well as in the Cellular and Vesicular Proteomes of the Acholeplasma laidlawii in Adapting the Bacterium to Different Environmental Conditions

For the first time as a result of the comparative analysis of proteomes of cells and extracellular vesicles, as well as the complete nucleotide sequence of Acholeplasma laidlawii cells under various conditions of growth of the mycoplasma, the evidence of a high level of plasticity of this bacterium,...

Full description

Saved in:
Bibliographic Details
Published in:BioNanoScience 2017-06, Vol.7 (2), p.323-325
Main Authors: Mouzykantov, A. A., Medvedeva, E. S., Malygina, T. Y., Baranova, N. B., Davydova, M. N., Siniagina, M. N., Boulygina, E. A., Mahmud, R. Shah, Prottoy, R. A., Trushin, M. V., Chernova, O. A., Chernov, V. M.
Format: Article
Language:English
Subjects:
Biological and Medical Physics
Biomaterials
Biophysics
Circuits and Systems
Comparative analysis
CRISPR
Engineering
Environmental conditions
Nanotechnology
Nucleotide sequence
Plastic properties
Plasticity
SOS response
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:For the first time as a result of the comparative analysis of proteomes of cells and extracellular vesicles, as well as the complete nucleotide sequence of Acholeplasma laidlawii cells under various conditions of growth of the mycoplasma, the evidence of a high level of plasticity of this bacterium, providing a rapid adaptation to stressors associated with the SOS response, was obtained. The battery of genes with targeted potential for the infekta control system using CRISPR tools was revealed.
ISSN:2191-1630
2191-1649
DOI:10.1007/s12668-016-0362-2