Efficient Synthesis of 5‐Carboxanilide‐Dihydropyrimidinones Using Cobalt(II) Nitrate Hexahydrate

5‐Carboxanilide‐dihydropyrimidinone derivatives were synthesized in good yield in a three‐component and efficient process by the condensation reaction of acetoacetanilide, aldehyde and urea/thiourea in the presence of cobalt(II) nitrate hexahydrate as catalyst in ethanol at ambient condition. 5‐Carb...

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Bibliographic Details
Published in:Journal of the Chinese Chemical Society (Taipei) 2017-05, Vol.64 (5), p.481-485
Main Authors: Kangan, Mehrnoush, Hazeri, Nourallah, Yazdani‐Elah‐Abadi, Afshin, Maghsoodlou, Malek‐Taher
Format: Article
Language:English
Subjects:
5‐Carboxanilide‐dihydropyrimidinones
Acetoacetanilide
Acetoacetanilides
Aldehydes
Catalysts
Cobalt compounds
Cobalt(II) nitrate hexahydrate
Ethanol
Thioureas
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Summary:5‐Carboxanilide‐dihydropyrimidinone derivatives were synthesized in good yield in a three‐component and efficient process by the condensation reaction of acetoacetanilide, aldehyde and urea/thiourea in the presence of cobalt(II) nitrate hexahydrate as catalyst in ethanol at ambient condition. 5‐Carboxanilide‐dihydropyrimidinone derivatives were synthesized in good yield in a three‐component and efficient process by condensation reaction of acetoacetanilide, aldehyde, and urea/thiourea in the presence of cobalt(II) nitrate hexahydrate as catalyst in ethanol at ambient condition.
ISSN:0009-4536
2192-6549
DOI:10.1002/jccs.201600841