Inside Back Cover: A Tandem Enzymatic sp2‐C‐Methylation Process: Coupling in Situ S‐Adenosyl‐l‐Methionine Formation with Methyl Transfer (ChemBioChem 11/2017)

The inside back cover picture shows a one‐pot tandem reaction involving in situ enzymatic synthesis of S‐adenosylmethionine by using SalL, followed by C−C bond formation by using the C‐methyltransferase NovO. This system is compatible with both methionine and methionine analogues as the alkyl donor....

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Bibliographic Details
Published in:Chembiochem : a European journal of chemical biology 2017-06, Vol.18 (11), p.1050-1050
Main Authors: Sadler, Joanna C., Humphreys, Luke D., Snajdrova, Radka, Burley, Glenn A.
Format: Article
Language:English
Subjects:
Adenosylmethionine
alkylation
biocatalysis
Bonding
Cascade chemical reactions
Chemical synthesis
Compatibility
Coupling
Enzymatic synthesis
Methionine
Methylation
Methyltransferase
multi-enzyme reaction
S-Adenosylmethionine
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Summary:The inside back cover picture shows a one‐pot tandem reaction involving in situ enzymatic synthesis of S‐adenosylmethionine by using SalL, followed by C−C bond formation by using the C‐methyltransferase NovO. This system is compatible with both methionine and methionine analogues as the alkyl donor. More information can be found in the communication by L. D. Humphreys, G. A. Burley et al. on page 992 in Issue 11, 2017 (DOI: 10.1002/cbic.201700115).
ISSN:1439-4227
1439-7633
DOI:10.1002/cbic.201700244