Results of Pharmacotherapy of Attention Deficit Hyperactivity Disorder: Assessment Using Neuropsychological Methods

Study aim. To investigate the dynamics of measures of behavior, attention, and memory during treatment with Noofen (250-mg capsules) in children with attention deficit hyperactivity disorder (ADHD). Materials and methods. A total of 50 patients taking part in an open study were divided into two grou...

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Bibliographic Details
Published in:Neuroscience and behavioral physiology 2016-03, Vol.46 (3), p.354-359
Main Authors: Zavadenko, N. N., Suvorinova, N. Yu
Format: Article
Language:English
Subjects:
Attention deficit hyperactivity disorder
Behavioral Sciences
Biomedical and Life Sciences
Biomedicine
Children
Cognitive ability
Memory
Neurobiology
Neuropsychology
Neurosciences
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Summary:Study aim. To investigate the dynamics of measures of behavior, attention, and memory during treatment with Noofen (250-mg capsules) in children with attention deficit hyperactivity disorder (ADHD). Materials and methods. A total of 50 patients taking part in an open study were divided into two groups of 25 patients: patients of group 1 received Noofen while patients of group 2 (controls) received only low doses of multivitamins. Treatment lasted one month. Noofen was given at doses of 15–20 mg/kg (500–750 mg) per day using 250-mg capsules, as two or three doses. Results and conclusions. Neuropsychological test results at the end of one month of treatment demonstrated improvements in cognitive functions, including measures of self-control, sustained, focused, and distributed attention, and auditory verbal memory. It is suggested that the initial positive changes may provide a base for attaining more significant clinical outcomes with longer-lasting treatment.
ISSN:0097-0549
1573-899X
DOI:10.1007/s11055-016-0241-x