Intracoronary pressure measurement differences between anterior and posterior coronary territories

Introduction Intracoronary pressure measurements have improved assessment of angiographic intermediate coronary stenoses. Methodically, pressure equalization and actual measurements are frequently performed at different height levels, depending on the particular coronary territory analyzed. Consider...

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Bibliographic Details
Published in:Herz 2017-06, Vol.42 (4), p.395
Main Authors: Härle, T, Meyer, S, Bojara, W, Vahldiek, F, Elsässer, A
Format: Article
Language:English
Subjects:
Blood vessels
Coronary vessels
Equalization
Hydrostatic pressure
Lesions
Measurement methods
Patients
Population studies
Position measurement
Pressure
Pressure measurement
Stenosis
Stents
Supine position
Territory
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Summary:Introduction Intracoronary pressure measurements have improved assessment of angiographic intermediate coronary stenoses. Methodically, pressure equalization and actual measurements are frequently performed at different height levels, depending on the particular coronary territory analyzed. Considering a hypothetical influence of hydrostatic pressure and the supine position of the patient, differences in the results of intracoronary measurements between anterior and posterior vessels seem likely. The purpose of this study was to compare the results of intracoronary pressure measurements between anterior and posterior coronary territories. Methods Intracoronary pressure measurements of 214 coronary stenoses in 158 patients were analyzed. Fractional flow reserve (FFR) was measured in all stenosis and instantaneous wave-free ratio (iFR) in 197 stenoses in 144 patients. Results Both FFR (0.79 vs. 0.87, p < 0.001) and iFR values (0.86 vs. 0.94, p < 0.001) were significantly higher in posterior compared to anterior coronary vessels. Patients with only anterior or posterior lesions did not differ regarding clinical or lesion characteristics, in particular coronary stenosis severity (62.5 vs. 61.6 %, p = 0.27). Conclusions Results of intracoronary measurements were systematically higher in the posterior coronary vessels when compared with anterior vessels. This phenomenon was independent of coronary stenosis severity or any clinical characteristics in our study population.
ISSN:0340-9937
1615-6692
DOI:10.1007/s00059-016-4471-z