Construction of Redox Responsive Vesicles Based on a Supra-Amphiphile for Enzyme Confinement

Redox responsive vesicles were constructed based on guest interaction between fl-cyclodextrin and a ferrocene self-assembly of a supra-amphiphile built by the host- derivative. The structure and destruction-reconstruction reversibility of the ＂smart＂ vesicles were clearly characterized by electron m...

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Bibliographic Details
Published in:Chinese journal of chemistry 2017-06, Vol.35 (6), p.871-875
Main Authors: Pan, Tiezheng, Zou, Huixin, Sun, Hongcheng, Liu, Yao, Liu, Shengda, Luo, Quan, Dong, Zeyuan, Xu, Jiayun, Liu, Junqiu
Format: Article
Language:English
Subjects:
Biocompatibility
Confinement
Construction
Controlled release
Cyclodextrin
Destruction
Electron microscopy
Enzymes
glutathione S‐transferase
host‐guest systems
Light scattering
Photon correlation spectroscopy
Protease
Proteinase
Reconstruction
redox responsive
Self-assembly
supra‐amphiphile
Vesicles
分子结构
动态光散射技术
双亲分子
氧化还原反应
生物相容性
电子显微镜
相互作用
蛋白酶抗性
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Summary:Redox responsive vesicles were constructed based on guest interaction between fl-cyclodextrin and a ferrocene self-assembly of a supra-amphiphile built by the host- derivative. The structure and destruction-reconstruction reversibility of the ＂smart＂ vesicles were clearly characterized by electron microscopy and dynamic light scattering. Notably, these vesicles were proved to be capable of controlled release function and bringing protease resistance to the enzyme, showing great biocompatibility and promising applications.
ISSN:1001-604X
1614-7065
DOI:10.1002/cjoc.201600772