From polydisperse diatomaceous earth to biosilica with specific morphologies by glucose gradient/dialysis: a natural material for cell growth

Starting from polydisperse diatomaceous earth (DE), we proposed an efficient separation method for obtaining different morphologies of biosilica from diatoms. DE is a very low-cost source of silica containing all the differently nanostructured elements. By a glucose gradient/dialysis, three types of...

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Bibliographic Details
Published in:MRS communications 2017-06, Vol.7 (2), p.214-220
Main Authors: Cicco, S.R., Vona, D., Leone, G., Lo Presti, M., Palumbo, F., Altamura, E., Ragni, R., Farinola, G.M.
Format: Article
Language:English
Subjects:
Biocompatibility
Biomaterials
Biomedical materials
Cell growth
Characterization and Evaluation of Materials
Clusters
Dialysis
Diatomaceous earth
Ethanol
Fluorescence
Glucose
Hemodialysis
Hydroxyapatite
Materials Engineering
Materials Science
Morphology
Nanotechnology
Osteoblasts
Plankton
Platforms
Polymer Sciences
Research Letter
Research Letters
Rods
Scaffolds
Scraping
Sedimentation & deposition
Separation
Silicon dioxide
Topography
Valves
Water resistance
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Summary:Starting from polydisperse diatomaceous earth (DE), we proposed an efficient separation method for obtaining different morphologies of biosilica from diatoms. DE is a very low-cost source of silica containing all the differently nanostructured elements. By a glucose gradient/dialysis, three types of biosilica morphologies were achieved: rods, valves, and clusters. We fully characterized the diatom fractions and we used them to produce fluorescent biosilica platforms (“tabs”). These supports exhibited good resistance in water, ethanol, and soft scraping. A preliminary biologic application by testing Saos-2 proliferation was also performed to check osteoblasts-like cells biologic attitude for this scaffolds with tunable nanostructure.
ISSN:2159-6859
2159-6867
DOI:10.1557/mrc.2017.27