Optimal Model Based Control for Blood Glucose Insulin System Using Continuous Glucose Monitoring

[...]continuous monitoring and control of glucose level is necessary for Type 1 diabetes patients. The digestion process considered as slow process (dead time process) while consume the food, automatically the blood glucose level in the blood is changed, for type 1 diabetic to injection of insulin f...

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Bibliographic Details
Published in:Journal of pharmaceutical sciences and research 2017-04, Vol.9 (4), p.465
Main Authors: Sivaramakrishnan, N, Lakshmanaprabu, S K, Muvvala, M Vamsikrishna
Format: Article
Language:English
Subjects:
Closed loop systems
Control algorithms
Controllers
Decision making
Diabetes
Fuzzy logic
Genetic algorithms
Genetic engineering
Glucose
Glucose monitoring
Human body
Insulin
Mathematical models
Pancreas
Patients
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Summary:[...]continuous monitoring and control of glucose level is necessary for Type 1 diabetes patients. The digestion process considered as slow process (dead time process) while consume the food, automatically the blood glucose level in the blood is changed, for type 1 diabetic to injection of insulin from insulin pump in exact quantity. A genetic algorithm based PID control algorithm is proposed to control blood glucose level effectively in type 1 diabetics. The artificial pancreas (a closed loop control system) enables diabetic patient to maintain normal glucose level by providing the right amount of insulin at the right time with no need for human interaction when it comes to decision making. In some advanced control techniques to combined the two types of controllers like proportional integral derivative (PID), and fuzzy logic controllers (FLC) and control the blood glucose level. If glucose is not breakdown it is increase it tends to hyperglycemia (high blood sugar) it can lead to blindness and some heart problems.Type-1 diabetic patients the pancreas is not functioning and it is not injecting the insulin naturally so artificially to inject the insulin for those patients to regulate the glucose level. [...]3.3g/minutes pulse is applied in simulation for 15 minutes. Blood glucose control algorithms for type 1 diabetic patients:A methodological review,Katrin Lunze a, Tarunraj Singh b, Marian Walter a, Mathias D. Brendel, Steffen Leonhardt a Department of Electrical Engineering, RWTH Aachen University, Aachen 52074, Germany [10].
ISSN:0975-1459