Ocular surface involvement on GVHD patients

Purpose To identify the different complications of GVHD on ocular surface. Methods Ocular examen de surface sur les patients atteints de GVHD, visé par le centre de l'os greffe de moelle d'Alger, tous bénéficié de OSDI Questionnaire, fente examen à la lampe, la coloration fluorescéine et t...

Full description

Saved in:
Bibliographic Details
Published in:Acta ophthalmologica (Oxford, England) England), 2016-10, Vol.94 (S256), p.n/a
Main Author: Lazreg, S.
Format: Article
Language:English
Subjects:
Acuity
Coloration
Complications
Cornea
Eye
Graft-versus-host reaction
Males
Ophthalmology
Staining
Visual acuity
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Purpose To identify the different complications of GVHD on ocular surface. Methods Ocular examen de surface sur les patients atteints de GVHD, visé par le centre de l'os greffe de moelle d'Alger, tous bénéficié de OSDI Questionnaire, fente examen à la lampe, la coloration fluorescéine et test de Schirmer, Results 31 patients were assessed, 22 males, tha mean age value were 39.3 years ± 7.4; all patients presented different levels of severity of dry eye at slit lamp examination, 5% of them had a very low visual acuity; Mean OSDI score was 76.4 ± 10.2 corneal staining was present on 92% of cases (oxford: 6.5 ± 2.5) and Schirmer value 10 ± 5.4). Conclusions Dry eye is the most common ocular complication on GVHD patients, in most of cases it is a severe dry eye with corneal involvement and visual impairment, an early diagnosis and treatment of ocular manifestations of GVHD is essential to prevent severe complications.
ISSN:1755-375X
1755-3768
DOI:10.1111/j.1755-3768.2016.0392