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Correlation between retinal and mixed venous oxygen saturation

Purpose To investigate the correlation between mixed venous (SvO2) and retinal vessel (SrO2) oxygen saturation, using non‐invasive spectroscopy in pre‐ and post‐ heart transplant patients. Methods Retinal oxygen saturation and vessel caliber were measured in dark‐adapted patients, breathing ambient...

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Bibliographic Details
Published in:Acta ophthalmologica (Oxford, England) England), 2016-10, Vol.94 (S256), p.n/a
Main Authors: Van Keer, K., Abegão Pinto, L., Stalmans, I., Vandewalle, E.
Format: Article
Language:English
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Summary:Purpose To investigate the correlation between mixed venous (SvO2) and retinal vessel (SrO2) oxygen saturation, using non‐invasive spectroscopy in pre‐ and post‐ heart transplant patients. Methods Retinal oxygen saturation and vessel caliber were measured in dark‐adapted patients, breathing ambient air in a seated position, using dual wavelength retinal oximetry, within 24 h of a SvO2 sampling during right heart catheterization. Correlations were analyzed using Pearson correlation coefficients and linear regression models. Results Twelve patients aged 57.4 ± 18.2 years were analyzed. A strong negative correlation was found between retinal arteriovenous oxygen difference and SvO2 (r = −0.64, p = 0.024), as well as between retinal arterial diameter and time since heart transplantation (r = −0.77, p = 0.009), independent of demographic and systemic parameters. Conclusions Retinal oximetry provides a non‐invasive method to visualize and quantify the oxygen saturation of arteries and veins of the central circulatory system. This pilot study provides proof of concept for the use of retinal oximetry in the follow‐up of patients after heart transplantation, to assess cardiac function as well as cardiovascular health.
ISSN:1755-375X
1755-3768
DOI:10.1111/j.1755-3768.2016.0650