Score of Toxic Epidermal Necrosis Predicts the Outcomes of Pediatric Epidermal Necrolysis

Background/Objectives Epidermal necrolysis (Stevens–Johnson syndrome and toxic epidermal necrolysis) includes immune‐mediated, life‐threatening inflammatory blistering disorders that can affect children. The Score of Toxic Epidermal Necrosis (SCORTEN) tool has accurately predicted the outcome of the...

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Bibliographic Details
Published in:Pediatric dermatology 2017-07, Vol.34 (4), p.433-437
Main Authors: Sorrell, Jennifer, Anthony, Lisa, Rademaker, Alfred, Belknap, Steven M., Callahan, Shields, West, Dennis P., Paller, Amy S.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Child
Child, Preschool
Children
Cohort Studies
Female
Gangrene
Humans
Length of Stay - statistics & numerical data
Male
Necrosis
Pediatrics
Prognosis
Retrospective Studies
Severity of Illness Index
Stevens-Johnson syndrome
Stevens-Johnson Syndrome - diagnosis
Toxic epidermal necrolysis
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Summary:Background/Objectives Epidermal necrolysis (Stevens–Johnson syndrome and toxic epidermal necrolysis) includes immune‐mediated, life‐threatening inflammatory blistering disorders that can affect children. The Score of Toxic Epidermal Necrosis (SCORTEN) tool has accurately predicted the outcome of these disorders in adults but has not been tested in children. Methods We performed a retrospective chart review to compare the accuracy of the adult SCORTEN tool with that of two modifications tailored to children in predicting disease outcome. Results The longer the patient's median length of hospital stay was, the higher the adult and two proposed pediatric SCORTENs were. In addition, all patients who died had SCORTENs greater than 4. Conclusion The pediatric‐modified tools were not superior to the adult SCORTEN, which accurately predicted outcome.
ISSN:0736-8046
1525-1470
DOI:10.1111/pde.13172