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Effect of human albumin on corrosion and biological behavior of CoCrMo

The present paper is an investigation of human albumin effect on corossion and biological behavior of a CoCrMo alloy The electrochemical behavior of the alloy was tested in SBF with and without HSA. The used electrochemical methods have been open circuit potential measurement, potentiodynamic polari...

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Bibliographic Details
Published in:Materials and corrosion 2017-08, Vol.68 (8), p.876-882
Main Authors: Ionita, D., Golgovici, F., Demetrescu, I., Sajin, M., Pandelea‐Dobrovicescu, G.‐R.
Format: Article
Language:English
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Summary:The present paper is an investigation of human albumin effect on corossion and biological behavior of a CoCrMo alloy The electrochemical behavior of the alloy was tested in SBF with and without HSA. The used electrochemical methods have been open circuit potential measurement, potentiodynamic polarization, and electrochemical impedance spectroscopy. Albumin adsorption has been evaluated spectrophotometrically using both FT–IR and UV–VIS investigation methods. The human albumin acts as an inhibitor of corrosion reducing corrosion current until five time. The mechanism of inhibition is due to a protective barrier based on a complex metal‐protein formation and evidenced by impedance spectroscopy procedure. Biological tests confirmed non hemocompatibility of CoCrMo alloy and a non trombogenic behavior. No blood cell shape modification was observed as well. The present paper is an investigation of human albumin effect on corossion and biological behavior of a CoCrMo alloy. The human albumin act as an inhibitor of corrosion reducing corrosion current until five time. Biological tests confirmed non hemocompatibility of CoCrMo alloy and a non trombogenic behaviour. No blood cell shape modification was observed as well.
ISSN:0947-5117
1521-4176
DOI:10.1002/maco.201609406