Inside Cover: Lipid Nanotube Tailored Fabrication of Uniquely Shaped Polydopamine Nanofibers as Photothermal Converters (Chem. Eur. J. 13/2016)

Helically‐coiled polydopamine (PDA) nanofibers were fabricated on a lipid nanotube (LNT) as an efficient photothermal converter for cancer therapy. The incorporation of anionic oleic acid was critical for the absorption and polymerization of dopamine on the helical marks of LNT. The coiled PDA‐LNT h...

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Bibliographic Details
Published in:Chemistry : a European journal 2016-03, Vol.22 (13), p.4298-4298
Main Authors: Ding, Wuxiao, Chechetka, Svetlana A., Masuda, Mitsutoshi, Shimizu, Toshimi, Aoyagi, Masaru, Minamikawa, Hiroyuki, Miyako, Eijiro
Format: Article
Language:English
Subjects:
Absorbance
Cancer
Chemistry
Coiling
Converters
Dopamine
Fabrication
Irradiation
morphology effect
Nanofibers
Nanostructure
nanotube
Oleic acid
photothermal
Photothermal conversion
polydopamine
Polymerization
template synthesis
Tumor cells
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Summary:Helically‐coiled polydopamine (PDA) nanofibers were fabricated on a lipid nanotube (LNT) as an efficient photothermal converter for cancer therapy. The incorporation of anionic oleic acid was critical for the absorption and polymerization of dopamine on the helical marks of LNT. The coiled PDA‐LNT hybrid showed higher light absorbance and photothermal conversion effect than the linear and spherical counterparts. In cellular experiments, the coiled PDA‐LNT could also efficiently associate with tumor cells and eliminate HeLa cells after laser irradiation. More information can be found in the Communication by W. Ding, E. Miyako et al. on page 4345 ff.
ISSN:0947-6539
1521-3765
DOI:10.1002/chem.201600559