A35 SEVERE ASTHMA: Characteristics Of Patients With Severe, Uncontrolled, Eosinophilic Asthma Enrolled In An Observational French Cohort (cobra)

Methods: COhort BRonchial obstruction and Asthma (COBRA) is a prospective cohort study of patients with asthma at French tertiary care centers, followed-up every 6 months for 10 years. At study inclusion, patients eligible for benralizumab had a lower pre-bronchodilator forced expiratory volume in 1...

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Bibliographic Details
Published in:American journal of respiratory and critical care medicine 2017-01, Vol.195
Main Authors: Aubier, M, Thabut, G, Fabry-Vendrand, C
Format: Article
Language:English
Subjects:
Asthma
Health risk assessment
Monoclonal antibodies
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Summary:Methods: COhort BRonchial obstruction and Asthma (COBRA) is a prospective cohort study of patients with asthma at French tertiary care centers, followed-up every 6 months for 10 years. At study inclusion, patients eligible for benralizumab had a lower pre-bronchodilator forced expiratory volume in 1 second (69.8% of predicted value [standard deviation {SD} 18.3] vs. 74.4% [SD 22.9]) and less effective asthma control (optimal in 4.7% vs. 19.5%; Asthma Control Test scores 11.2 [SD 4.5] vs. 13.2 [SD 5.8]), compared with patients who did not meet the eligibility criteria for benralizumab treatment.
ISSN:1073-449X
1535-4970