A35 SEVERE ASTHMA: Age Of Asthma Onset Differentiates Two Very Severe Asthma Phenotypes In The Severe Asthma Research Program

EOA3 had the most severe allergic asthma with poor baseline lung function and persistent airflow obstruction despite marked reversibility to albuterol (mean pre-BD FEV1%predicted=46%, post-BD FEV1=60%). The remaining 37% of subjects were assigned to two groups with Adult Onset Asthma (AOA1-2) with m...

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Bibliographic Details
Published in:American journal of respiratory and critical care medicine 2017-01, Vol.195
Main Authors: Moore, W C, Li, X, Li, H, Israel, E, Fitzpatrick, A M, Mauger, D, Phillips, B, Sorkness, R L, Wu, W, Wenzel, S E, Meyers, D, Bleecker, E
Format: Article
Language:English
Subjects:
Asthma
Cluster analysis
Health risk assessment
Health services utilization
Online Access:Get full text
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Summary:EOA3 had the most severe allergic asthma with poor baseline lung function and persistent airflow obstruction despite marked reversibility to albuterol (mean pre-BD FEV1%predicted=46%, post-BD FEV1=60%). The remaining 37% of subjects were assigned to two groups with Adult Onset Asthma (AOA1-2) with mean disease diagnosis of 35 years, frequent sinusitis (43-46%), nasal polyposis (33%) and sinus surgery (19-23%) but less atopy (62-65% with >1 positive spIgE).
ISSN:1073-449X
1535-4970