C74 ADVANCES IN TRANSLATIONAL COPD: Effects Of Chronic Smoking Exposure On The Lung And Cecal Microbiomes In Mice

Methods: Adult mice were exposed to air (control group) or 3 cigarettes per day, 5 days per week (smoked group) for 6 months (n=30 per group), using a standard nose-only smoke exposure system. Results: Cigarette smoke exposure was not associated with changes in total 16S counts (copies/ng of DNA), w...

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Bibliographic Details
Published in:American journal of respiratory and critical care medicine 2017-01, Vol.195
Main Authors: Filho, F Leitao, Ra, S, Tam, A, Yang, J, Ngan, D A, Wright, J, Churg, A, Sze, M, Leung, J, Man, S P, Sin, D D
Format: Article
Language:English
Subjects:
Chronic obstructive pulmonary disease
Deoxyribonucleic acid
DNA
Lungs
Smoking
Tobacco smoke
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Summary:Methods: Adult mice were exposed to air (control group) or 3 cigarettes per day, 5 days per week (smoked group) for 6 months (n=30 per group), using a standard nose-only smoke exposure system. Results: Cigarette smoke exposure was not associated with changes in total 16S counts (copies/ng of DNA), when compared to the air-exposed controls in lungs or guts (p>0.05).
ISSN:1073-449X
1535-4970