A33 CLINICAL STUDIES IN OBSTRUCTIVE LUNG DISEASE: Association Of Platelet Count And Aspirin Use With COPD Morbidity: The Spiromics And COPDgene Cohorts

Elevated platelet count has been associated with increased all-cause mortality in COPD patients while aspirin was associated with reduced mortality and slower progression of subclinical emphysema. Methods: Among participants with COPD (GOLD stage I-IV) from two multi-center observational studies (SP...

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Bibliographic Details
Published in:American journal of respiratory and critical care medicine 2017-01, Vol.195
Main Authors: Fawzy, A, Putcha, N, Paulin, L M, Aaron, C P, Labaki, W W, Han, M K, Wise, R A, Kanner, R E, Bowler, R, Barr, R G, Hansel, N N
Format: Article
Language:English
Subjects:
Aspirin
Chronic obstructive pulmonary disease
Health risk assessment
Morbidity
Mortality
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Summary:Elevated platelet count has been associated with increased all-cause mortality in COPD patients while aspirin was associated with reduced mortality and slower progression of subclinical emphysema. Methods: Among participants with COPD (GOLD stage I-IV) from two multi-center observational studies (SPIROMICS and COPDGene), reported frequency of acute exacerbations of COPD (AECOPD) in previous year, six-minute-walk distance (6MWD), St. George Respiratory questionnaire (SGRQ), modified Medical Research Council (mMRC) dyspnea scale, and CBC with platelet count were collected at baseline (SPIROMICS) or 5-year visit (COPDGene).
ISSN:1073-449X
1535-4970