A31 MECHANISMS IN CYSTIC FIBROSIS AND OTHER BRONCHIECTATIC DISEASES: Loss Of Cftr Alters Alveolar Macrophage Viral Defense

Corresponding author's email: tgauthi@emory.edu Rationale: Respiratory viral infections from pathogens such as respiratory syncytial virus (RSV) or human rhinovirus (HRV) are associated with increased pulmonary exacerbations in both young children and adult patients with cystic fibrosis (CF). M...

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Bibliographic Details
Published in:American journal of respiratory and critical care medicine 2017-01, Vol.195
Main Authors: Gauthier, T W, Ping, X, Anderson, L J, Moore, M L, Brown, L
Format: Article
Language:English
Subjects:
Cystic fibrosis
Females
Respiratory syncytial virus
Rodents
Viral infections
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Summary:Corresponding author's email: tgauthi@emory.edu Rationale: Respiratory viral infections from pathogens such as respiratory syncytial virus (RSV) or human rhinovirus (HRV) are associated with increased pulmonary exacerbations in both young children and adult patients with cystic fibrosis (CF). Methods: Neonatal mouse AM (post natal day 10) and adult AM (males or females) were isolated via bronchoalveolar lavage from C57Bl6 cftr KO (S489X) gut corrected mice and their wild type littermates (WT) after genotyping.
ISSN:1073-449X
1535-4970