C73 NEW MECHANISMS AND THERAPIES IN COPD: Involvement Of Extracellular Atp In Mucus Production During Rhinovirus Infection

[Rationale and Objectives] In response to tissue damage or inflammation, adenosine triphosphate (ATP) is released into the extracellular compartment and has been demonstrated to augment inflammation via purinergic P2 receptors. C)], a synthetic analog of dsRNA used to mimic viral infection, in NCI-H...

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Bibliographic Details
Published in:American journal of respiratory and critical care medicine 2017-01, Vol.195
Main Authors: Aizawa, H, Koarai, A, Shishikura, Y, Yamaya, M, Sugiura, H, Watanabe, M, Hashimoto, Y, Numakura, T, Makiguchi, T, Abe, K, Yamada, M, Kikuchi, T, Hoshikawa, Y, Okada, Y, Ichinose, M
Format: Article
Language:English
Subjects:
Chronic obstructive pulmonary disease
Infections
Viral infections
Online Access:Get full text
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Summary:[Rationale and Objectives] In response to tissue damage or inflammation, adenosine triphosphate (ATP) is released into the extracellular compartment and has been demonstrated to augment inflammation via purinergic P2 receptors. C)], a synthetic analog of dsRNA used to mimic viral infection, in NCI-H292 cells and differentiated airway epithelial cells from COPD patients.
ISSN:1073-449X
1535-4970