D99 BEST FROM THE LAB IN SDB: MECHANISMS AND BEYOND: Inflammation And Contractility Are Altered By Obstructive Sleep Apnea Children's Serum, In Human Embryonic Stem Cell Derived Cardiomyocytes

In order to investigate NF-kB activation and the physiology of cardiomyocytes of human origin, we have established an ex-vivo model where human cardiomyocytes derived from human embryonic stem cells were incubated with OSAS and control sera. Human cardiomyocytes were derived from the human embryonic...

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Bibliographic Details
Published in:American journal of respiratory and critical care medicine 2017-01, Vol.195
Main Authors: Goldbart, A, Ophir, R, Rabinski, T, Gopas, J
Format: Article
Language:English
Subjects:
Cardiomyocytes
Embryos
Inflammation
Pediatrics
Sleep apnea
Stem cells
Online Access:Get full text
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Summary:In order to investigate NF-kB activation and the physiology of cardiomyocytes of human origin, we have established an ex-vivo model where human cardiomyocytes derived from human embryonic stem cells were incubated with OSAS and control sera. Human cardiomyocytes were derived from the human embryonic stem cell H-9.1 clone (hEsC H9.1).
ISSN:1073-449X
1535-4970