A77 CHANGES IN THE LUNG DUE TO DIETARY AND ENVIRONMENTAL EXPOSURES: Does A 90-Day Exposure To Aldehydes Impair Respiratory Function And Structure?

[...]we aimed to investigate the response of mice lung and nasal epithelium to exposure (8 h/day, 90 days) to environmental relevant concentrations of formaldehyde (200 ppb, FA group), acetaldehyde (500 ppb, AC group), mixtures 1 (M1 group: 250 ppb FA + 3 ppm AC) or 2 (M2 group: 250 ppb FA + 0.7 ppm...

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Published in:American journal of respiratory and critical care medicine 2017-01, Vol.195
Main Authors: Zin, W A, Abreu, M, Neto, A C, Carvalho, G M, Casquilho, N V, Carvalho, N, Okuro, R T, Motta-Ribeiro, G C, Machado, M N, Cardozo, A, Silva, A S, Barboza, T, Rodrigues, D A, Camilo, L M, Carneiro, L, Jandre, F, Pino, A V, Giannella-Neto, A, Travassos, L H, Souza, M N, Roncally-Carvalho, A
Format: Article
Language:English
Subjects:
Rodents
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Summary:[...]we aimed to investigate the response of mice lung and nasal epithelium to exposure (8 h/day, 90 days) to environmental relevant concentrations of formaldehyde (200 ppb, FA group), acetaldehyde (500 ppb, AC group), mixtures 1 (M1 group: 250 ppb FA + 3 ppm AC) or 2 (M2 group: 250 ppb FA + 0.7 ppm AC). [...]tissue damping and elastance, airway resistance, and inertance were determined.
ISSN:1073-449X
1535-4970